Autoimmune diseases (ADs) are a heterogeneous group of diseases
affecting up to 10% of the population whereas cancer is one of the
leading causes of morbidity and mortality worldwide.
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In Japan a significant number of adolescent girls complain of unusual symptoms after Human Papillomavirus (HPV) vaccination, and these symptoms, composed of orthostatic dysregulation, Chronic Regional Pain Syndrome (CRPS) and cognitive dysfunction are considered adverse effects of HPV vaccination.
Hyperprolactinemia is a relatively common endocrinopathy seen in
clinical practice, with prevalence ranging from 0.4% in healthy population to 5% in family planning clinics. Pregnancy and lactation are the most common causes of physiologic hyperprolactinemia with levels up to 207 ng/mL being reported.
Silicone may, like any other adjuvant, induce an inflammatory reaction and diseases. There is no data about its use in renal transplant recipients.
In the 1980s, as consumer concern regarding silicone breast implant safety grew, the U.S. Food and Drug Administration’s new surveillance system began to identify local complications associated with silicone implants in addition to several published case reports that described an association between cancer and connective tissue disorders in patients with these devices.
The Pregnancy and Lactation Autoimmune Network (PLAN) registry was established to evaluate the concerns of women with autoimmune or inflammatory rheumatic diseases (AIRD) pertaining to pregnancy and lactation
Giant-cell arteritis (GCA) is the most frequent form of vasculitis in patients over the age of 50. Large- and medium-sized vessels are mainly affected, especially the cranial branches of the external carotid. The aorta and its branches are also involved in 30 to 60% of patients.
Unprecedented successes regarding cancer immunotherapy have been achieved, in which therapeutic agents are used to targeting immune cells rather than cancer cells.
Prolactin (PRL) elevation in patients with prolactin-secreting pituitary tumors has been linked to an increased prevalence of thyroid autoantibodies. However, the effects of antipsychotic drug-induced hyperprolactinemia (HPRL) on the development of thyroid autoimmunity and also of other autoimmune phenomena have not been previously studied.
A growing number of studies have investigated the malignancy risk associated with systemic lupus erythematosus (SLE), and our review will focus mainly (though not exclusively) on studies published in the past year.