Here, we discuss features of the mammalian immune system that enable it to orchestrate variable inflammatory responses that maintain and heal the body while protecting it from pathogenic infectious agents and tumors.
5 days ago
Objective. To clarify the prevalence, risk factors, outcome, and outcome-related factors of hemophagocytic lymphohistiocytosis (HLH) in patients with dermatomyositis (DM), polymyositis (PM), or clinically amyopathic dermatomyositis (CADM).
5 days ago
Gout is a common inflammatory joint disease worldwide, in part
because the global prevalence of gout was rising. The direct
relationship between the elevated levels of uric acid and gout
attack is well-recognized. Several risk factors for gout attacks are
found, including dietary factors, medications, and comorbidities.
12 days ago
Rheumatoid arthritis (RA) is an autoimmune disease caused by genetic and environmental factors. Infection is proposed to contribute to the pathogenesis. Several viral and bacterial infections, including parvovirus B19, Chikungunya, hepatitis C, Epstein-Barr virus and Porphyromonas gingivalis, have been raised to be associated with RA
14 days ago
The objective was to develop evidence-based recommendations for the management of antiphospholipid syndrome (APS) in adults. Based on evidence from a systematic literature review and expert
opinion, overarching principles and recommendations
were formulated and voted.
Recurrent pericarditis is one of the main complications of acute
pericarditis that affects approximately 20–50% of all patients with
acute pericarditis . It usually occurs after the first episode of acute pericarditis with a symptom-free interval of 4–6 weeks. The specific etiology includes infectious, neoplastic, autoimmune, or autoinflammatory causes, but in 70% of the cases, the etiology remains unknown.
The human papillomavirus (HPV) vaccination programme aims to prevent cervical cancer. Globally around 13.1/100,000 women are diagnosed with cervical cancer each year.2 Typically, vaccination is offered to girls aged 9–13 years before sexual debut and naı¨ve to HPV infection. Box 1 gives an overview of licensing and indications in Europe and the US.
To report the clinical course and identification of rodenticide in a patient who smoked synthetic cannabinoids and developed coagulopathy, correlated with the identification of rodenticides in synthetic cannabinoid drug samples provided by the patient
We read with interest the study published by Braaten and
colleagues, analyzing the long-term outcomes of 60 patients
developing persistent inflammatory arthritis (IA) after immune
checkpoint inhibitors (ICIs) cessation.
Connective tissue diseases (CTDs) are a group of chronic and disabling diseases that involve inappropriate or excessive immune responses. They include a wide variety of illnesses such as rheumatoid arthritis (RA), systemic sclerosis (SSc), systemic lupus
erythematosus (SLE) and Sjo¨gren’s syndrome (SS)