Resveratrol (RSV), a naturally occurring polyphenol, has been found to have potent antioxidant, anti-inflammatory, and anticancer effects. Recently, RSV was reported as a new potential agent to suppress inflammation of collagen-induced arthritis in a mouse model. Nevertheless, the clinical benefits of RSV in the management of rheumatoid arthritis (RA) were not studied.
4 days ago
Pollution has long been incriminated in many cardiovascular and respiratory diseases. More recently, studies evaluated the potential role for particulate pollutants in autoimmune diseases, including rheumatoid arthritis (RA)
4 days ago
14-3-3h may represent a useful diagnostic biomarker for rheumatoid arthritis (RA). We assessed the prevalence and serum levels of 14-3- 3h in patients with RA and in patients with other rheumatic diseases. Serum levels of 14-3-3h were measured in 96 patients with RA, in 101 patients with other rheumatic diseases, and in 66 healthy subjects.
6 days ago
Rheumatoid arthritis (RA) is characterised by functional disability,
pain, fatigue and body composition alterations that can further
impact on the physical dysfunction seen in RA. RA is also associated with systemic manifestations, most notably an increased risk
for cardiovascular disease
11 days ago
Autoimmune rheumatic diseases are characterised by an abnormal immune system response, complement activation, cytokines dysregulation and inflammation.
Our objective was to investigate whether a dietary pattern derived using inflammatory biomarkers is associated with rheumatoid arthritis (RA) risk. We prospectively followed 79,988 women in the Nurses’ Health Study (NHS, 1984–2014) and 93,572 women in the NHSII (1991–2013); incident RA was confirmed by medical records.
In rheumatoid arthritis (RA), immunological triggers at mucosal sites, such as the gut microbiota, may promote autoimmunity that affects joints.
Smoking is Associated with low levels of soluble PD-L1 in Rheumatoid Arthritis
The safety of treatment with biological disease-mod- ifying antirheumatic drugs (bDMARD) has been carefully studied for the past 15 years; however, it is still largely unknown whether this treatment is safe in patients with arthritis with a history of cancer.
This study found no association between the presence of ACPAs, other autoantibodies commonly occurring in rheu- matological diseases, or cigarette smoking, and lymphoma risk in RA. These results suggest that other mechanisms are involved in the development of lymphoma in patients with RA, and that the search for biomarkers that can predict development of lymphoma in RA must be continued.