We read with interest the study published by Braaten and
colleagues, analyzing the long-term outcomes of 60 patients
developing persistent inflammatory arthritis (IA) after immune
checkpoint inhibitors (ICIs) cessation.
Regular physical activity (PA) is increasingly promoted for people with rheumatic and musculoskeletal diseases as well as the general population. This article provides the evaluation of if the public health recommendations for PA are applicable for people with inflammatory arthritis (iA; Rheumatoid Arthritis and Spondyloarthritis) and osteoarthritis (hip/knee OA) in order to develop evidence-based recommendations for advice and guidance on
PA in clinical practice.
Increased permeability of the gut wall lumen, leading to exposure of the immune system to microorganisms. This may lead to an immune response that, via haematological spread, results in a local inflammatory process within the joints. Note: gut microbiome composition can be affected by: age, drug use, comorbidity, malnutrition, diet, infections and stress.