The human papillomavirus (HPV) vaccination programme aims to prevent cervical cancer. Globally around 13.1/100,000 women are diagnosed with cervical cancer each year.2 Typically, vaccination is offered to girls aged 9–13 years before sexual debut and naı¨ve to HPV infection. Box 1 gives an overview of licensing and indications in Europe and the US.
Human papillomavirus（HPV）ワクチンの接種後にSLE を発症した一例
To identify clinical and quantitative relationship between vaccinations and small fiber neuropathy (SFN). SFN refers to damaged unmyelinated or thinly myelinated sensory and/or autonomic fibers. Diagnosis is primarily based on clinical presentation. Intraepidermal nerve fiber density can provide diagnostic confirmation with a sensitivity of 88% and a specificity of 91%. However, the possible association between vaccination and small fiber polyneuropathy is not well defined.
H1N1 vaccination in Sjögren’s syndrome triggers polyclonal B cell activation and promotes autoantibody production.
Objectives Vaccination of patients with rheumatic disease has been reported to result in lower antibody titres than in healthy individuals. However, studies primarily include patients on immunosuppressive therapy. Here, we investigated the immune response of treatment-naïve patients diagnosed with primary
Sjögren’s syndrome (pSS) to an H1n1 influenza vaccine.
The emergence of autoimmunity after vaccination has been described in many case reports and series. Everyday there is more evidence that this relationship is more than casual. In humans, adjuvants can induce non-speciﬁc constitutional, musculoskeletal or neurological clinical manifestations
Murine hypothalamic destruction with vascular cell apoptosis subsequent to combined administration of human papilloma virus vaccine and pertussis toxin