Anti-OJ autoantibodies are myositis-specific autoantibodies (MSAs)
that can be found in < 5% of patients with idiopathic inflammatory
myopathies (IIMs). They presumably target isoleucyl-tRNA synthetase and, as such, are part of the group of the anti-aminoacyl-tRNA synthetases, of which anti-Jo-1 is the most prevalent.
There is an increased interest in the reproductive health of patients with rheumatic diseases. The potential reproductive health issues include reduced sexual libido, sexual disability, subfertility/infertility, low fecundity, and reduced family size.
Patients with idiopathic inflammatory myopathies (IIMs) suffer an increased burden of comorbidities, but data on mortality in recently diagnosed IIM are conflicting. Also, little is known when, if ever, in relation to IIM diagnosis, mortality is increased.