Tag: antibodies
Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases (collectively referred to as myositis), which mainly include the subtypes of polymyositis, dermatomyositis, immune-mediated necrotizing myopathy (IMNM) and sporadic inclusion body myositis (sIBM).
9 days ago
 
Hypothyroidism induced by an autoimmune process is associated with neuropsychiatric symptoms and metabolic abnormalities in the brain. The aim of this study was to examine the relationship between autoimmune thyroiditis and regional brain function in hypothyroid patients.
25.09.2019
 
Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases (collectively referred to as myositis), which mainly include the subtypes of polymyositis, dermatomyositis, immune-mediated necrotizing myopathy (IMNM) and sporadic inclusion body myositis (sIBM).
23.08.2019
 
Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was observed in Sweden following mass-vaccination with PandemrixVR. Genetic association to HLA DQB106:02 implies an autoimmune origin, but target autoantigen remains unknown.
16.08.2019
 
G-protein-coupled receptors (GPCRs) are the largest family of receptors in humans. GPCRs are seven-transmembrane receptors that are activated by the binding of a ligand to the extracellular domain. In addition to the endogenous ligands, auto-antibodies (aab) can also bind to the GPCRs. They can activate different and specific cellular pathways which contribute to various diseases
14.06.2019
 
Janus kinase (JAK) inhibitors are a relatively new addition to our tools for treatment of rheumatoid arthritis (RA)1. They are responsible for transduction of more than 38 cytokinases2, with diffuse metabolic/immunologic implications.
26.04.2019
 
Presence of circulating antinuclear antibodies (ANAs) in patient serum is widely regarded as the hallmark of systemic autoimmune rheumatic disease [1]. A request for a serological ANA screening test is usually a first step for the laboratory diagnosis
18.02.2019
 
Close to 30 years ago we [Y.S. et al.] came up with the notion that autoimmune diseases share a common background which they had termed the mosaic of autoimmunity.
20.12.2018
 
Autoantibodies to the dense fine speckled 70 (DFS70) antigen are common among antinuclear antibodies (ANA) positive healthy individuals (HI). We assessed the prevalence of anti-DFS70 antibodies in patients with and without ANA-associated rheumatic diseases (AARDs) by two methods: chemiluminescent immunoassay (CIA) and an indirect immunofluorescence (IIF) assay based on immunoadsorption for DFS70.
08.11.2018
 
The treatment of autoimmune disease is a challenge and priority as they affect 50 million individuals in the United States, and currently they collectively are the third most common disease category.
03.10.2018