Tag: antibodies
We have read with great interest the article by Ryabkova et al. [1], which discuss the current knowledge about the presence of autoantibodies and their role as pathogenic drivers in cardiovascular disease, with a specific emphasis on the risk of “… lethal episodes of arrhythmias provoking fatal acute heart failure” and sudden cardiac death.
15.01.2020
 
Hashimoto encephalopathy (HE), also known as steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), is characterized by various neuropsychiatric symptoms, the presence of serum anti-thyroid antibodies, and responsiveness to immunotherapies.
02.12.2019
 
Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases (collectively referred to as myositis), which mainly include the subtypes of polymyositis, dermatomyositis, immune-mediated necrotizing myopathy (IMNM) and sporadic inclusion body myositis (sIBM).
07.10.2019
 
Hypothyroidism induced by an autoimmune process is associated with neuropsychiatric symptoms and metabolic abnormalities in the brain. The aim of this study was to examine the relationship between autoimmune thyroiditis and regional brain function in hypothyroid patients.
25.09.2019
 
Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases (collectively referred to as myositis), which mainly include the subtypes of polymyositis, dermatomyositis, immune-mediated necrotizing myopathy (IMNM) and sporadic inclusion body myositis (sIBM).
23.08.2019
 
Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was observed in Sweden following mass-vaccination with PandemrixVR. Genetic association to HLA DQB106:02 implies an autoimmune origin, but target autoantigen remains unknown.
16.08.2019
 
G-protein-coupled receptors (GPCRs) are the largest family of receptors in humans. GPCRs are seven-transmembrane receptors that are activated by the binding of a ligand to the extracellular domain. In addition to the endogenous ligands, auto-antibodies (aab) can also bind to the GPCRs. They can activate different and specific cellular pathways which contribute to various diseases
14.06.2019
 
Janus kinase (JAK) inhibitors are a relatively new addition to our tools for treatment of rheumatoid arthritis (RA)1. They are responsible for transduction of more than 38 cytokinases2, with diffuse metabolic/immunologic implications.
26.04.2019
 
Presence of circulating antinuclear antibodies (ANAs) in patient serum is widely regarded as the hallmark of systemic autoimmune rheumatic disease [1]. A request for a serological ANA screening test is usually a first step for the laboratory diagnosis
18.02.2019
 
Close to 30 years ago we [Y.S. et al.] came up with the notion that autoimmune diseases share a common background which they had termed the mosaic of autoimmunity.
20.12.2018