The gut microbiome is increasingly recognized as having fundamental roles in human physiology and health. A central question is the extent to which microbiome composition is determined by host genetics. Previous studies have identified several heritable bacterial taxa but the combined bacterial abundance accounted for by them has not yet been quantified.
This study received funding from the Swedish Foundation for Strategic Research, the Swedish Research Council, the Swedish COMBINE public-private research programme, the Swedish Cancer
Society, the Lions Cancer Research Foundation in Uppsala, the Swedish Rheumatism Association, the EU-IMI BT Cure project, King Gustaf V's 80 year Foundation, SFO Epidemiology at Karolinska Institutet, and Stockholm County Council.